Leadership Profile

Vittorio Gallo, PhD

Director, DC-IDDRC
Dr. Gallo is Professor of Pediatrics, Pharmacology and Physiology at GWU, and has a joint appointment in Pharmacology at GU. He has been Director of the AC, and Director of the DC-IDDRC/PI of the P30 Award since July 2007. Dr. Gallo has also been Director of the Center for Neuroscience Research (CNR) and has held the Wolf-Pack Chair of Neuroscience at CNHS since 2002. He obtained his Ph. D. from the University of Rome and completed his thesis work with Dr. Giulio Levi and Nobel laureate Rita Levi-Montalcini at the Italian National Research Council. He trained as a postdoctoral fellow at the Medical Research Council-Developmental Neurobiology Unit, at University College London, and at the NIMH Laboratory of Preclinical Pharmacology. He won several awards from the European Molecular Biology Organization and later from NATO. Before joining CNHS, he was senior Investigator at NICHD, where he directed the Section on Molecular and Cellular Neurobiology. Dr. Gallo’s research focuses on gliogenesis and neurogenesis in the postnatal brain. His recent work has expanded into the field of neural stem/progenitor cells and their potential for perinatal brain regeneration and repair. His work has also evolved into neurobiological studies of IDD through his investigation of: i) white matter development and function after perinatal hypoxia, and ii) the potential use of postnatal neural stem cells to regenerate specific classes of neurons and glia after demyelination or hypomyelination. Dr. Gallo’s current NIH awards support 3 different research programs: i) identifying neural progenitor cells in the postnatal subventricular zone, and defining their developmental properties and lineage potential (1R01NS045702); ii) defining the role of specific transcription factors in oligodendrocyte development and regeneration (1R01NS056427); and iii) characterizing the molecular and cellular pathways that promote white matter repair and functional recovery after perinatal hypoxia/hyperoxia (1R21NS095351). He is also the PI of the T32 Training Program in IDDR (T32HD046388). Dr. Gallo has authored more than 120 peer-reviewed articles, many in high impact international journals (Nature, Nature Neuroscience, Neuron, Cell Reports, The Journal of Cell Biology, PNAS, The Journal of Neuroscience), and 30 review articles and book chapters (Neuron, Nature Neuroscience). He is on the editorial boards of Nature Neuroscience, The Journal of Neuroscience (Reviewing Editor) and Glia. In his current position as Director of the CNR, he also plays a major mentorship role for both junior faculty and fellows, many of them supported by career development awards.

William Gaillard, MD

Co-Director, DC-IDDRC
Dr. Gaillard joined the faculty of Children’s National in 1993. He earned his medical degree at Yale University. After completing internship and residency in Pediatrics at the Children’s Hospital in Pittsburgh and Neurology residency at Johns Hopkins Hospital, he completed a fellowship in Epilepsy, Clinical Neurophysiology, and Imaging at NINDS. Dr. Gaillard has been the Associate Director of CNR at CRI since 2003. He is also Chief of the Divisions of Child Neurology, Epilepsy, Neurophysiology, and Critical Care Neurology. He is Professor of Pediatrics and Neurology at GWU, and Professor of Neurology at GU. A pediatrician, neurologist, and epileptologist by training, Dr. Gaillard has worked throughout his career to study the effect of disease states on brain structure and function, with a particular emphasis on epilepsy. He currently directs brain-imaging initiatives in pediatric developmental disorders in addition to his continuing work in epilepsy. Dr. Gaillard has specific expertise in imaging modalities and their application to pediatric populations including structural and functional imaging with MRI, and PET. He has pioneered functional (BOLD) MRI in developmental cognitive neuroscience and translated experimental findings to change clinical practice. He has published 140 peer reviewed articles and 63 chapters/reviews, and edited three books. Dr. Gaillard has had an established and synergistic collaboration with Dr. Gallo for the past 13 years, and continues to play a crucial role in mentorship of junior DC-IDDRC investigators.